The Psychedelic Brain

Sam Harris speaks with neuroscientist Robin Carhart-Harris about the progress and ongoing challenges of psychedelic research and psychedelic therapy. They discuss the REBUS model—relaxed beliefs under psychedelics; why patients with the lowest expectations show the strongest response to psilocybin; recovered memory, trauma, and the risks of therapist bias; 5-MeO-DMT and its use among underground therapists; the neuroscience of ego dissolution; and other topics.